I heard Chris Townsend on a podcast recently championing wool over synthetics. Especially when worn under a garment. Especially on longer hikes.
On one of his reviews of hiking socks:
Smartwool Hiking is my first choice with the well-priced Fox River Trailmaster a very close second.
Townsend routinely wears a different sock on each foot in order to compare them.
besthike.com 